Sources of Informaion on HNPCC


1.  Aaltonen, Lauri A.  Molecular Genetic Background of Hereditary Nonpolyposis Colorectal Cancer.  1996.

2.  Bellacosa, A.; Genuardi, M.; Anti, M.; Viel, A.; Ponz de Leon, M. Hereditary nonpolyposis colorectal cancer: review of clinical, molecular genetics, and counseling aspects. American  Journal of Medical Genetics. 62: 353-364.

3.  Bronner, C. E.; et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 368: 258-261, 1994.

4.  HNPCC Reference Guide.

5.  Lindblom, A., Tannergard, P., Werelius, B. & Nordenskjold, M.  Genetic mapping of a second locus
predisposing to hereditary non-polyposis colon cancer.  Nature Genetics.  5, 279-282 (1993).

6.  Lynch, Henry T., et al. Living with Hereditary Colorectal Cancer. Omaha, Nebraska: Creighton University.

7.  Lynch, Henry T., and Jane F. Lynch.  The Lynch Syndrome: Melding Natural History and Molecular Genetics to Genetic Counseling and Cancer Control.

8.  Lynch, H. T.; Smyrk, T. C.; Watson, P., et al.Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review. Gastroenterology. 1993; 104: 1535-1549

9.  Lynch, Patrick M.  Discovery of an HNPCC Gene. 1993.

10.  Memorial Sloan-Kettering Cancer Center.  Colon Cancer.  1997.

11.  National Center for Biological Information.  COLON CANCER, FAMILIAL, NONPOLYPOSIS TYPE 2.  1998.

12.  National Center for Biological Information.  Colon Cancer, nonpolyposis, type 2.  1998.

13.  Nystom-Lahti, M., Sistonen, P., Mecklin, J. Pylkkanen, L., Aaltonen, L., Jarvinen, H., Weissenbach, J., Chapelle, A. & Peltomaki, P.  Close linkage to chromosome 3p and conservation of ancestral founding haplotype in hereditary nonpolyposis colorectal cancer families.  Proc. Natl. Acad. Sci. USA.  91, 6054-6058 (1994).

14.  Papadopoulus, Nickolas, Nicholas C. Nicolaides, Ying-Fei Wing, Steven M. Ruben, Kenneth C. Carter, Craig A. Rosen, William A. Haseltine, Robert D. Fleischmann, Claire M. Fraser, Mark D. Adams, J. Craig Venter, Stanley R. Hamilton, Gloria M. Peterson, Patrice Watson, Henry T. Lynch, Paivi Peltomaki, Jukka-Pekka Mecklin, Albert de la Chapelle, Kenneth W. Kinzler, and Bert Vogelstein.  "Mutation of a mutL Homolog in Hereditary Colon Cancer".  Science 263.  1994.

15.  Prolla,T.A., D.M. Christie and R.M. Liskay.  "Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene."  Molecular Cellular Biology.  407-415.  1994.

16.  South Denver Gastoenterology.  Colon Cancer.

17.  Thibodeau, S.N, et. al.  Sequence Analysis and Protein Expression of hMSH2 and hMLH1 in Sporadic and Inherited Colon Cancer.

18.  Watson, James, Michael Gilman, Jan Witkowski, and Mark Zoller.  Recombination of DNA.  Scientific American Books: New York.  1992.



DePauw University HNPCC Home Page

Created by:  April Bardes, Colin Connor, and Allison Niggemyer, Biology Department, DePauw University, Bios 354:  Molecular Genetics, Spring 1998.