The schedule below outlines each day's main topic(s). Reading assignments from Analytical Chemistry 2.1 (listed as AC2.1), links to additional reading assignments, and links to useful files are listed after the topic; see below for a list of useful explanatory codes.
Getting Started
- January 30:
no class: university closed
- February 1: course introduction
Unit One
In which we review selected topics from Chem 260, learn to visualize equilibrium systems and how to determine the composition of a system at equilibrium using mathematical models of varying complexity.
- February 6: review of equilibrium chemistry and thermodynamics (read AC2.1: 6A-E)
- February 8: ladder diagrams for acid-base, complexation, and redox reactions (read AC2.1: 6F, 6H.2)
- February 13: developing a systematic approach to modeling an acid-base system (read AC2.1: 6G.3)
- February 15: using R to model an acid-base system (read AC2.1: 6J)
- February 20: solubility and pH (read AC2.1: 8.B1)
- February 22: solubility and complexation (read AC2.1: 8.B1)
- February 27: case study: binding of Cu2+ by glycine (read AC2.1: none)
- March 1: case study: metal absorption on oxide surfaces (read AC2.1: none)
- March 6: activity effects, or why equilibrium constants are not constant (read AC2.1: 6K)
- March 8:
no class (take-home unit exam distributed; due Friday, March 15th)
Unit Two
In which we a develop a general theory of analytical separations and use it to design separations based on liquid-liquid extractions.
- March 13: general theory of analytical separations (read AC2.1: 7E, 7F.5)
- March 15: simple liquid-liquid extractions (read AC2.1: 7G.1-2)
- March 20: liquid-liquid extractions involving acids and bases (read AC2.1: 7G.3)
- March 22: liquid-liquid extractions involving metal-ligand complexes (read AC2.1: 7G.4)
- March 27:
Spring Break
- March 29:
Spring Break
- April 3: continuous liquid-liquid extractions (read AC2.1: 12A.1-2, Appendix 16)
- April 5: continuous liquid-liquid extractions (read AC2.1: 12A.1-2, Appendix 16)
- April 10: catch-up and review (take-home unit exam distributed; due Friday, April 19th)
- April 12:
no class (take-home unit exam in progress)
Unit Three
In which we develop a general theory of chromatography and use it to optimize separations based on gas chromatography and liquid chromatography.
- April 17: general theory of chromatography (read AC2.1: 12B)
- April 19: general theory of chromatography (read AC2.1: 12B)
- April 24: general theory of chromatography (read AC2.1: 12B
- April 26: gas chromatography and liquid chromatography (read AC2.1: 12D,E)
- May 1: optimizing a separation by focusing on efficiency (read AC2.1: 12C.1)
- May 3: optimizing a separation by focusing on selectivity (read AC2.1: 12C.2)
- May 8: optimizing a separation by focusing on retention (read AC2.1: 12C.3)
- May 9: take-home unit exam sent out by email; due Thursday, May 16th